覃映雪
发布时间:2017-02-18 浏览次数:  文章作者:


一、基本情况

覃映雪,女,1976年生,教授,博士,主要从事微生物分子遗传及鱼类病害与免疫防治研究。近年来主持和参与多项国家级、省部级、市厅级科研项目。目前已在国内外学术期刊《Fish & Shellfish Immunology》、《Frontiers in Cellular and Infection Microbiology》、《Microbial Pathogenesis》、《Genetics and Molecular Research》、《Gene》等中外期刊发表30多篇研究论文,其中SCIEI收录十余篇,并获国家发明专利1项。

电子邮箱:yxqin@jmu.edu.cn

二、教育经历

● 2000/7 - 2005/8,厦门大学,海洋系,硕博连读,获博士学位

● 1995/9 - 1999/7,厦门大学,海洋系,学士

三、工作经历:

● 2016/11 – 至今,集美大学,水产学院,教授

● 2014/08 - 2015/8,Public Health Research Institute Center, Dept. Microbiology & Molecular Genetics, New Jersey Medical School Rutgers, The State University of New Jersey,访问学者

● 2008/11 – 2016/11, 集美大学,水产学院,副教授

● 2005/08 – 2008/11,集美大学,水产学院,讲师

四、主持和参与的课题

LuxR家族调控蛋白对嗜水气单胞菌在鳗鲡巨噬细胞内存活的调控及机制研究国家自然科学基金青年基金项目,31502194),2016.1-2018.12,经费额22.56万元

● 斜带石斑TRL2介导的MyD88依赖型信号通路对肠道菌群变化的响应(福建省自然科学基金2013J01137),2013-2015,经费额5万元

●    rpoS基因在溶藻弧菌感染过程中的功能及其调控机制(国家自然科学基金项目,31672694),2017.1-2020.12,经费额62万元

● 国家海洋局:海洋药源生物种质资源库建设课题子课题(12PYY001SF08-JMDX-1), 2015.01-2016.12, 经费额40万元

● 溶藻弧菌对大黄鱼粘附作用的基因调控研究(国家自然科学基金,31272699),2013.1-2016.12,经费额75万元

海洋渔用疫苗工程技术研究中心(海洋经济区域创新发展示范项目,14PYY050SF03),2014.7-2015.12,经费额1169.37万元

●  海水鱼益生菌及海水净化微生物制剂开发与产业化(厦门市海洋经济发展专项资金项目,14CZP032HJ06),2014.7-2016.12,经费199.85万元

海水养殖鱼类原籍饲用益生菌开发(厦门市科技计划项目,3502Z20133016),2012.12-2014.12,经费额15万元

水产品中大肠杆菌快速定量检测规程制定(厦门市海洋与渔业局科技项目,201357),2013.1-2014.6,20万元

石斑鱼主要病原弧菌的趋化性及分子机制研究(福建省青年创新基金资助项目 2006F3096),2007.1-2009.12 4 万元

● 饲料用酶——新型木聚糖酶(科技部科技型中小企业技术创新基金 07C26223511509),20072009,经费额80万;

海洋环境主要病原微生物现场监测的免疫磁珠液相芯片系统(国家863计划2007AA09Z115),2007-2010,经费额:59.4

五、发表文章及申请专利

● 苏永全,王德祥,王军,丁少雄,覃映雪.大黄鱼线粒体分子标记及用于养殖群体与野生种群的鉴别.中华人民共和国国家知识产权局.2006.7.26 专利号:ZL 2004 1 0060149.5

Yingxeu Qin, Guifang Lin, Wenbo Chen, Xiaojin Xu, Qingpi Yan. Flagellar motility is necessary for Aeromonas hydrophila adhesion. Microbial Pathogenesis, 2016, 98:160-166

Ying-Xue Qin, Gui-Fang Lin, Wen-Bo Chen, Bei Huang, Wenshu Huang, Qing-pi Yan. Flagellar motility contributes to the invasion and survival of Aeromonas hydrophila in Anguilla japonica macrophage. Fish and Shellfish Immunology, 2014,39(2): 273-279

●  Song S X, Ding S X, Yan Q P, Qin Y X (Correspondent author). Complete mitochondrial  genome of Sipunculus nudus (Sipuncula, Sipunculidae)[J]. Mitochondrial DNA, 2016272):1022-1023.

W.B. Zeng, W.B. Chen, Q.P. Yan, G.F. Lin, Y.X. Qin(Correspondent author). Hemerythrin is required for Aeromonas hydraphlia to survive in macrophages of Anguilla japonica. Genetics and Molecular Research, 2016, 15(2): DOI http://dx.doi.org/10.4238/gmr.15028074. (2016. 05)

Y.X. Qin, Q.P. Yan, X.X. Mao, Z. Chen, Y.Q.Su. Role of MshQ in MSHA pili biosynthesis and biofilm formation of Aeromonas hydrophila. Genetics and Molecular Research, 2014, 13(4): 8982 -8996.

Qin Yingxue, Yan Qingpi, Su Yongquan, Li Haiping, Zou Wenzheng. Disruption of chemotaxis-related genes affects multiple cellular processes and the virulence of pathogenic Vibrio harveyi. Acta Oceanologica Sinica, 2013, 32(8): 55-60.

Lu Wang, Lixing Huang, Yongquan Su, Yingxue Qin, Wendi Kong, Ying Ma, Xiaojin Xu, Mao Lin, Qingpi Yan*. Involvement of the flagellar assembly pathway in Vibrio alginolyticus adhesion under environmental stresses. Frontiers in Cellular and Infection Microbiology, 2015, 5, article 59: 1-9.

Lixing Huang, Jiao Hu, Yongquan Su, Yingxue Qin, Wendi Kong, Lingmin Zhao, Ying Ma, Xiaojin Xu, Mao Lin, Jiang Zheng, Qingpi Yan*. Genome-wide detection of predicted non-coding RNAs related to the adhesion process in Vibrio alginolyticus using high-throughput sequencing. Frontiers in Microbiology, 2016, 7, article 619: 1-10

Lixing Huang, Li Huang, Qingpi Yan*, Yingxue Qin, Ying Ma, Mao Lin, Xiaojin Xu, Jiang Zheng. The TCA Pathway is an Important Player in the Regulatory Network Governing Vibrio alginolyticus Adhesion Under Adversity. Frontiers in Microbiology, 2016, 7, article 40: 1-13

Lixing Huang, JiaoHu, YongquanSu, YingxueQin, WendiKong, YingMa, Xiaojin Xu, MaoLin and Qingpi Yan*. Identification and characterization of three Vibrio alginolyticus non-coding RNAs involved in adhesion, chemotaxis, and motility processes. Frontiers in Cellular and Infection Microbiology, 2015, 5, article 56: 1-13.

Xiaojin  Xu, Yingxue Qin, Gang Luo, Xi Huang, Wen-zheng Zou, Jun Wang , Yongquan Su. Ontogeny of digestive organs during early developmental stages of the tropical whitespotted bamboo shark, Chiloscyllium plagiosum – a histological study. Marine and Freshwater Behaviour and Physiology, 2015 48(4): 253-266SCI.

徐晓津, 桑本红, 覃映雪, 邹文政,毛勇,邹峰,罗罡,苏永全. 大黄鱼刺激隐核虫病组织中巨噬细胞移动因子的检测. 中国水产科学, 2015, 22(6): 1227-1233.2015-11-15

Li Huang, Yingxue Qin, Qingpi Yan, Guifang Lin, Lixing Huang, Bei Huang, Wenshu Huang. MinD plays an important role in Aeromonas hydrophila adherence to Anguilla japonica mucus. Gene, 2015,5652:275-281. 2015-7-10

Wendi Kong, Lixing Huang, Yongquan Su, Yingxue Qin, Ying Ma, Xiaojin Xu, Mao Lin, Jiang Zheng. Qingpi Yan. Ivestigation of possible molecular mechanisms underlying the regulation of adhesion in Vibrio alginolyticus with comparative transcriptome analysis. Antonie van Leeuwenhoek, 2015, 107:1197-1206.

Jiang X, Qin Yingxue, Lin GF, Huang L, Huang B, Huang WS, Yan QP. FlgN plays important roles in the adhesion of Aeromonas hydrophila to host mucus. Genetics and Molecular Research, 2014, 14(2): 6376-6386.

邰光富, 鄢庆枇, 徐晓津, 李芊, 覃映雪(通讯作者). 鳗鲡外周血白细胞体外吞噬嗜水气单胞菌数量模型的建立. 渔业科学进展, 2013, 34(6):68-74.

覃映雪,赵敏慧,苏永全,王军,张小东,王晓露,鄢庆枇. 绿色荧光蛋白标记的病原性河流弧菌在青石斑肠道的粘附定植研究. 海洋学报,2012,34(6):170-176.

覃映雪,徐晓津,鄢庆枇,苏永全,刘力铭,李学刚. 转座子mini-Tn10介导的运动突变对溶藻弧菌毒力的影响. 水产学报, 2012, 367):1126-1132.

林桂芳,鄢庆枇,陈文博,苏永全,覃映雪(通讯作者). 间接ELISA法研究嗜水气单胞菌对鳗鲡表皮黏液的黏附特性. 中国水产科学, 2013, 20(5): 1023-1031.

● 19、Wenbo Chen, Yingxue Qin, Xiaojin Xu, Ying Ma, Zhen Chen, Yongquan Su, Qingpi Yan. Effects of NG-monomethyl-L-arginine (NMMA) and catalase on intracellular survival of Vibrio alginolyticus in macrophages of large yellow croaker Pseudosciaena crocea. African Journal of Microbiology Research, 2012, 6(12): 2941-2948.

● 20、Wang S F, Cai Y, Qin Y X, Zhou Y C, Su Y Q, Wang J. Characterization of yellow grouper Epinephelus awoara ( Serranidae) karyotype by chromosome bandings and fluorescence in situ hybridization. Journal of Fish Biology, 2012, 80(4): 866-875.

● 21、李海平,鄢庆枇,徐晓津,苏永全,覃映雪(通讯作者).哈维氏弧菌生物被膜体外模型的建立及成膜特性研究. 热带海洋学报, 2011,303):99-104.

● 22、毛秀秀, 覃映雪,邹文政,郭松林,苏永全,鄢庆枇,纪荣兴. 致病性嗜水气单胞菌生物膜的形成特性. 中国水产科学, 2011, 18(2): 371-378.

● 23、陈珍, 覃映雪, 邹文政,徐晓津,邢颜丽,鄢庆枇. 致病性副溶血弧菌成膜特性研究[J]. 海洋学报, 2010,32(5): 110-116.

● 24、Qin Yingxue,Su Yongquan,Yan Qingpi, Wang Shifeng. Immunogenicity and Protective Efficacy of Vibrio harveyi pcFlaA DNA Vaccine in Epinephelus awoara.Chinese Journal of Oceanology and Limnology, 2009, 27(4):769-774.

● 25、刘力铭,钱爱霞,鄢庆枇,覃映雪(通讯作者).哈维氏弧菌TS-628菌株趋化性研究.渔业科学进展,2010, 31(6):104-109.



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